Blar i forfatter "Hood, Kerenza"

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    • Antibiotic prescribing for acute Respiratory tract infections 12 months after communication and CRP training: a randomized trial 

      Little, Paul; Stuart, Beth; Francis, Nick A; Douglas, Elaine; Tonkin-Crine, Sarah; Anthierens, Sibyl; Cals, Jochen W L; Melbye, Hasse; Santer, Miriam; Moore, Michael; Coenen, Samuel; Butler, Christoffer C; Hood, Kerenza; Kelson, Mark; Godycki-Cwirko, Maciek; Mierzecki, Artur; Torres, Antoni; Llor, Carl; Davies, Melanie; Mullee, Mark; O'Reilly, Gilly; van der Velden, Alike; Geraghty, Adam; Goossens, Herman; Verheij, Theo; Yardley, Lucy (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03)
      <i>PURPOSE</i> - C-reactive-protein (CRP) is useful for diagnosis of lower respiratory tract infections (RTIs). A large international trial documented that Internet-based training in CRP point-of-care testing, in enhanced communication skills, or both reduced antibiotic prescribing at 3 months, with risk ratios (RRs) of 0.68, 0.53, 0.38, respectively. We report the longer-term impact in this ...

    • Are Patient Views about Antibiotics Related to Clinician Perceptions, Management and Outcome? A Multi-Country Study in Outpatients with Acute Cough 

      Coenen, Samuel; Francis, Nick; Kelly, Mark; Hood, Kerenza; Nuttal, Jacqui; Little, Paul; Verheij, Theo J. M.; Melbye, Hasse; Goossens, Herman; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Outpatients with acute cough who expect, hope for or ask for antibiotics may be more unwell, benefit more from antibiotic treatment, and be more satisfied with care when they are prescribed antibiotics. Clinicians may not accurately identify those patients. Objective: To explore whether patient views (expecting, hoping for or asking for antibiotics) are associated with illness presentation ...

    • Associations with antibiotic prescribing for acute exacerbation of COPD in primary care: Secondary analysis of a randomised controlled trial 

      Gillespie, David; Butler, Christopher C.; Bates, Janine; Hood, Kerenza; Melbye, Hasse; Phillips, Rhiannon; Stanton, Helen; Alam, Mohammed Fasihul; Cals, Jochen; Cochrane, Ann; Kirby, Nigel; Llor, Carl; Lowe, Rachel; Naik, Gurudutt; Riga, Evgenia; Sewell, Bernadette; Thomas-Jones, Emma; White, Patrick; Francis, Nick (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-26)
      <i>Background</i> - C-reactive protein (CRP) point-of-care testing can reduce antibiotic use in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in primary care, without compromising patient care. Further safe reductions may be possible.<br><br> <i>Aim</i> - To investigate the associations between presenting features and antibiotic prescribing in patients with ...

    • Associations with Post-Consultation Health-Status in Primary Care Managed Acute Exacerbation of COPD 

      Gillespie, David; Francis, Nick; Ahmed, Haroon; Hood, Kerenza; Llor, Carl; White, Patrick; Thomas-Jones, Emma; Stanton, Helen; Sewell, Bernadette; Phillips, Rhiannon; Naik, Gurudutt; Melbye, Hasse; Lowe, Rachel; Kirby, Nigel; Cochrane, Ann; Bates, Janine; Alam, Mohammed Fasihul; Butler, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-16)
      Background: It has been demonstrated that antibiotic prescribing for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) can be safely reduced in primary care when general practitioners have access to C-reactive protein (CRP) rapid testing.<p> <p>Aim: To investigate the factors associated with post-consultation COPD health status in patients presenting with AECOPD in this sett ...

    • C-reactive protein point-of-care testing for safely reducing antibiotics for acute exacerbations of chronic obstructive pulmonary disease: The PACE RCT 

      Francis, Nick; Gillespie, David; White, Patrick; Bates, Janine; Lowe, Rachel; Sewell, Bernadette; Phillips, Rhiannon; Stanton, Helen; Kirby, Nigel; Wootton, Mandy; Thomas-Jones, Emma; Hood, Kerenza; Llor, Carl; Cals, Jochen; Melbye, Hasse; Naik, Gurudutt; Gal, Micaela; Fitzsimmons, DF; Alam, Mohammed Fasihul; Riga, Evgenia; Cochrane, Ann; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03)
      Background - Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed antibiotics, but these may not be beneficial, and they can cause side effects and increase the risk of subsequent resistant infections. Point-of-care tests (POCTs) could safely reduce inappropriate antibiotic prescribing and antimicrobial resistance.<p> ...

    • C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations 

      Butler, Christopher C; Gillespie, David; White, Patrick; Bates, Janine; lowe, rachel; Thomas-Jones, Emma; Wootton, Mandy; Hood, Kerenza; Phillips, Rhiannon; Melbye, Hasse; Llor, Carl; Cals, Jochen W L; Naik, Gurudutt; Kirby, Nigel; Gal, Micaela; Riga, Evgenia; Francis, Nick A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
      <i>BACKGROUND</i> - Point-of-care testing of C-reactive protein (CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD).<p><p> <i>METHODS</i> - We performed a multicenter, open-label, randomized, controlled trial involving patients with a diagnosis of COPD in their primary care clinical ...

    • C-reactive protein-guided antibiotic prescribing for COPD exacerbations: A qualitative evaluation 

      Phillips, Rhiannon; Stanton, H.; Singh-Mehta, A.; Gillespie, David; Bates, Janine; Gal, Micaela; Thomas-Jones, Emma; Lowe, Rachel; Hood, Kerenza; Llor, Carl; Melbye, Hasse; Cals, Jochen; White, Patrick; Butler, Christopher C.; Francis, Nick (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
      Background - Antibiotics are prescribed to >70% of patients presenting in primary care with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The PACE randomised controlled trial found that a C-reactive protein point-of-care test (CRP-POCT) management strategy for AECOPD in primary care resulted in a 20% reduction in patient-reported antibiotic consumption over 4 weeks.<p> <p>Aim ...

    • Clinical Features and C-Reactive Protein as Predictors of Bacterial Exacerbations of COPD. 

      Francis, Nick A.; Gillespie, David; Wootton, M.; White, Patrick; Bates, Janine; Richards, J.; Melbye, Hasse; Hood, Kerenza; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-01)
      Introduction: Identifying predictors of bacterial and viral pathogens in sputum from patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) may help direct management.<p> <p>Methods: We used data from a trial evaluating a C-reactive protein (CRP) point of care guided approach to managing COPD exacerbations in primary care. We used regression analyses to identify ...

    • Clinical influences on antibiotic prescribing decisions for lower respiratory tract infection: a nine country qualitative study of variation in care. 

      Brookes-Howell, Lucy; Hood, Kerenza; Cooper, Lucy; Coenen, Samuel; Little, Paul; Verheij, Theo; Godycki-Cwirko, Maciek; Melbye, Hasse; Krawzyk, Jarek; Borras-Santos, A; Jakobsen, Kristin Alise; Worby, P; Goossens, Herman; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      There is variation in antibiotic prescribing for lower respiratory tract infections (LRTI) in primary care that does not benefit patients. This study aims to investigate clinicians' accounts of clinical influences on antibiotic prescribing decisions for LRTI to better understand variation and identify opportunities for improvement. Multi country qualitative interview study. Semi-structured interviews ...

    • Family practitioners' advice about taking time off work for lower respiratory tract infections: A prospective study in twelve European primary care networks 

      Godycki-Cwirko, M.; Nocun, Marek; Butler, Christopher C; Little, Paul; Verheij, Theo; Hood, Kerenza; Fleten, Nils; Kowalczyk, Anna; Melbye, Hasse (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      Background Acute cough and lower respiratory tract infections (LRTIs) are one of the most important causes of lost working hours. Aim to explore variation and predictors in family practitioners (FPs) advice to patients with LRTIs about taking time off work in different European countries. Methods Prospective observational study in primary care networks in 12 countries, with multilevel ...

    • Understanding variation in primary medical care: a nine-country qualitative study of clinicians' accounts of the non-clinical factors that shape antibiotic prescribing decisions for lower respiratory tract infection. 

      Brookes-Howell, Lucy; Hood, Kerenza; Cooper, Lucy; Little, Paul; Verheij, Theo; Coenen, Samuel; Godycki-Cwirko, Maciek; Melbye, Hasse; Borras-Santos, A; Worby, P; Jakobsen, Kristin Alise; Goossens, Herman; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      There is a wide variation between European countries in antibiotic prescribing for patients in primary care with lower respiratory tract infection (LRTI) that is not explained by case mix and clinical factors alone. Variation in antibiotic prescribing that is not warranted by differences in illness and clinical presentation may increase selection of resistant organisms, contributing to the problem ...